8222 : 5-{[4-(2-{[(E)-[1-(6-phenylpyridin-3-yl)ethylidene]amino]oxy}ethoxy)phenyl]methyl}-1,3-thiazolidine-2,4-dione
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8222 |
| Name | 5-{[4-(2-{[(E)-[1-(6-phenylpyridin-3-yl)ethylidene]amino]oxy}ethoxy)phenyl]methyl}-1,3-thiazolidine-2,4-dione |
| smile | C/C(/C1=CC=C(C2=CC=CC=C2)N=C1)=N\OCCOC1=CC=C(C=C1)CC1SC(NC1=O)=O |
| weight | 462 |
| scaffold ID | 1589 |
| scaffold smile | O=C1NC(=O)C(Cc2ccc(OCCON=Cc3ccc(-c4ccccc4)nc3)cc2)S1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8222 | 5-{[4-(2-{[(E)-[1-(6-phenylpyridin-3-yl)ethylidene]amino]oxy}ethoxy)phenyl]methyl}-1,3-thiazolidine-2,4-dione | 0.19 |
Scaffold Activities Statistic