8336 : 2-(2-{2-[(2S)-4-(5,5-difluorohexyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy}phenyl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8336 |
| Name | 2-(2-{2-[(2S)-4-(5,5-difluorohexyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy}phenyl)acetic acid |
| smile | CC(CCCCN1C([C@@H](OC2=CC=CC=C12)CCOC1=CC=CC=C1CC(O)=O)=O)(F)F |
| weight | 447 |
| scaffold ID | 61 |
| scaffold smile | O=C1Nc2ccccc2OC1CCOc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8336 | 2-(2-{2-[(2S)-4-(5,5-difluorohexyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy}phenyl)acetic acid | 1.0 |
Scaffold Activities Statistic