8446 : 2-[4-({2,6-bis[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8446 |
| Name | 2-[4-({2,6-bis[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1=CC(C2=CC=C(C(F)(F)F)C=C2)=NC(C2=CC=C(C(F)(F)F)C=C2)=N1 |
| weight | 562 |
| scaffold ID | 921 |
| scaffold smile | c1ccc(OCc2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8446 | 2-[4-({2,6-bis[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid | 10.0 |
Scaffold Activities Statistic