8457 : 2-[4-({2,6-bis[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid

Ligand Basic Message
LigandScaffold
ID8457
Name2-[4-({2,6-bis[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid
smileCC1=CC(=CC=C1OCC(O)=O)OCC1=CC(C2=CC=C(C=C2)OC(F)(F)F)=NC(C2=CC=C(C=C2)OC(F)(F)F)=N1
weight594
scaffold ID921
scaffold smilec1ccc(OCc2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1
Ligand Activities
NR ProteinProtein NameLigand IDLigand NameEC 50
NR1C3Peroxisome proliferator activated receptor gamma84572-[4-({2,6-bis[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl}methoxy)-2-methylphenoxy]acetic acid10.0
Scaffold Activities Statistic

Activities Statistic (6 ligands have same scaffold)