8459 : 2-{4-[({3,5-bis[4-(trifluoromethyl)phenyl]phenyl}methyl)sulfanyl]-3-chlorophenyl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8459 |
| Name | 2-{4-[({3,5-bis[4-(trifluoromethyl)phenyl]phenyl}methyl)sulfanyl]-3-chlorophenyl}acetic acid |
| smile | OC(CC1=CC=C(C(=C1)Cl)SCC1=CC(C2=CC=C(C(F)(F)F)C=C2)=CC(C2=CC=C(C(F)(F)F)C=C2)=C1)=O |
| weight | 581 |
| scaffold ID | 922 |
| scaffold smile | c1ccc(SCc2cc(-c3ccccc3)cc(-c3ccccc3)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8459 | 2-{4-[({3,5-bis[4-(trifluoromethyl)phenyl]phenyl}methyl)sulfanyl]-3-chlorophenyl}acetic acid | 10.0 |
Scaffold Activities Statistic