8535 : 2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8535 |
| Name | 2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid |
| smile | OC(CC1=CC=C(C=C1)CNC1=CC=CC(C2=C(C#N)C=NC3=C(C(F)(F)F)C=CC=C23)=C1)=O |
| weight | 461 |
| scaffold ID | 694 |
| scaffold smile | c1ccc(CNc2cccc(-c3ccnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8535 | 2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid | 0.45 |
Scaffold Activities Statistic