8536 : 2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8536 |
| Name | 2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid |
| smile | CC1=CN=C2C(C(F)(F)F)=CC=CC2=C1C1=CC=CC(=C1)NCC1=CC=C(C=C1)CC(O)=O |
| weight | 450 |
| scaffold ID | 694 |
| scaffold smile | c1ccc(CNc2cccc(-c3ccnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8536 | 2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid | 0.1 |
Scaffold Activities Statistic