8538 : N-(5-{1-[(4-methoxyphenyl)methyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8538 |
| Name | N-(5-{1-[(4-methoxyphenyl)methyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide |
| smile | COC1=CC=C(C=C1)CN1C(C2=CC=C3CC(NS(C4=CC=CC=C4)(=O)=O)CC3=C2)=CC2=CC=CC=C12 |
| weight | 509 |
| scaffold ID | 1223 |
| scaffold smile | O=S(=O)(NC1Cc2ccc(-c3cc4ccccc4n3Cc3ccccc3)cc2C1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8538 | N-(5-{1-[(4-methoxyphenyl)methyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide | 30.0 |
Scaffold Activities Statistic