8571 : 2-[(5-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)sulfamoyl]benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8571 |
| Name | 2-[(5-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)sulfamoyl]benzoic acid |
| smile | CC(OC(N1C(C2=CC=C3CC(NS(C4=CC=CC=C4C(O)=O)(=O)=O)CC3=C2)=CC2=CC=CC=C12)=O)(C)C |
| weight | 533 |
| scaffold ID | 41 |
| scaffold smile | O=S(=O)(NC1Cc2ccc(-c3cc4ccccc4[nH]3)cc2C1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8571 | 2-[(5-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)sulfamoyl]benzoic acid | 3.35 |
Scaffold Activities Statistic