8621 : 2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8621 |
| Name | 2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole |
| smile | FC1=CC=C(C2=C3C=CC=C(C(F)(F)F)C3=NN2CC2=CC=CC=C2Cl)C=C1 |
| weight | 405 |
| scaffold ID | 180 |
| scaffold smile | c1ccc(Cn2nc3ccccc3c2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8621 | 2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole | 2.89 |
Scaffold Activities Statistic