8624 : 3-(4-chlorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8624 |
| Name | 3-(4-chlorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole |
| smile | FC1=CC=CC=C1CN1N=C2C(C(F)(F)F)=CC=CC2=C1C1=CC=C(C=C1)Cl |
| weight | 405 |
| scaffold ID | 180 |
| scaffold smile | c1ccc(Cn2nc3ccccc3c2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8624 | 3-(4-chlorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole | 7.44 |
Scaffold Activities Statistic