8625 : 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8625 |
| Name | 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole |
| smile | FC1=CC=C(C(=C1)Cl)CN1N=C2C(C(F)(F)F)=CC=CC2=C1C1=CC=C(C=C1)Cl |
| weight | 439 |
| scaffold ID | 180 |
| scaffold smile | c1ccc(Cn2nc3ccccc3c2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8625 | 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole | 11.22 |
Scaffold Activities Statistic