8626 : 3-benzyl-4-{3-[3-(morpholine-4-carbonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8626 |
| Name | 3-benzyl-4-{3-[3-(morpholine-4-carbonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline |
| smile | FC(C1=CC=CC2=C(C3=CC=CC(=C3)OC3=CC=CC(C(N4CCOCC4)=O)=C3)C(=CN=C12)CC1=CC=CC=C1)(F)F |
| weight | 569 |
| scaffold ID | 745 |
| scaffold smile | O=C(c1cccc(Oc2cccc(-c3c(Cc4ccccc4)cnc4ccccc43)c2)c1)N1CCOCC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8626 | 3-benzyl-4-{3-[3-(morpholine-4-carbonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline | 0.138 |
Scaffold Activities Statistic