8641 : methyl 2-{5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1H-indol-3-yl}acetate
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8641 |
| Name | methyl 2-{5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1H-indol-3-yl}acetate |
| smile | COC(CC1=CNC2=CC=C(C=C12)OCCCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1)=O |
| weight | 635 |
| scaffold ID | 1062 |
| scaffold smile | c1cc2cc(OCCCN(Cc3ccccc3)CC(c3ccccc3)c3ccccc3)ccc2[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8641 | methyl 2-{5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1H-indol-3-yl}acetate | 0.288 |
Scaffold Activities Statistic