8642 : {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-4-yloxy)propyl]amine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8642 |
| Name | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-4-yloxy)propyl]amine |
| smile | FC(C1=CC=CC(=C1Cl)CN(CC(C1=CC=CC=C1)C1=CC=CC=C1)CCCOC1=CC=CC2NC=CC1=2)(F)F |
| weight | 563 |
| scaffold ID | 1061 |
| scaffold smile | c1cc2c(cccc2OCCCN(Cc2ccccc2)CC(c2ccccc2)c2ccccc2)[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8642 | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-4-yloxy)propyl]amine | 0.015 |
Scaffold Activities Statistic