8643 : {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(1-methanesulfonyl-1H-indol-4-yl)oxy]propyl}amine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8643 |
| Name | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(1-methanesulfonyl-1H-indol-4-yl)oxy]propyl}amine |
| smile | CS(N1C=CC2=C(C=CC=C12)OCCCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1)(=O)=O |
| weight | 641 |
| scaffold ID | 1061 |
| scaffold smile | c1cc2c(cccc2OCCCN(Cc2ccccc2)CC(c2ccccc2)c2ccccc2)[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8643 | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(1-methanesulfonyl-1H-indol-4-yl)oxy]propyl}amine | 0.007 |
Scaffold Activities Statistic