8649 : {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-5-yloxy)propyl]amine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8649 |
| Name | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-5-yloxy)propyl]amine |
| smile | FC(C1=CC=CC(=C1Cl)CN(CC(C1=CC=CC=C1)C1=CC=CC=C1)CCCOC1=CC=C2NC=CC2=C1)(F)F |
| weight | 563 |
| scaffold ID | 1062 |
| scaffold smile | c1cc2cc(OCCCN(Cc3ccccc3)CC(c3ccccc3)c3ccccc3)ccc2[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8649 | {[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-5-yloxy)propyl]amine | 0.023 |
Scaffold Activities Statistic