8652 : 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}aniline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8652 |
| Name | 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}aniline |
| smile | FC(C1=CC=CC(=C1Cl)CNC1=CC=CC(C2=C(N=NC3=C(C=CC=C23)Cl)CC2=CC=CC=C2)=C1)(F)F |
| weight | 538 |
| scaffold ID | 703 |
| scaffold smile | c1ccc(CNc2cccc(-c3c(Cc4ccccc4)nnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8652 | 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}aniline | 3.63 |
Scaffold Activities Statistic