8654 : 3-benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8654 |
| Name | 3-benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline |
| smile | FC1=CC=C(C(F)(F)F)C(=C1)COC1=CC=CC(C2=C(N=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1 |
| weight | 556 |
| scaffold ID | 154 |
| scaffold smile | c1ccc(COc2cccc(-c3c(Cc4ccccc4)nnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8654 | 3-benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline | 3.65 |
Scaffold Activities Statistic