8656 : 3-benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)cinnoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8656 |
| Name | 3-benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)cinnoline |
| smile | FC(C1=CC=CC(=C1Cl)COC1=CC=CC(C2=C(N=NC3=C(C=CC=C23)Cl)CC2=CC=CC=C2)=C1)(F)F |
| weight | 539 |
| scaffold ID | 154 |
| scaffold smile | c1ccc(COc2cccc(-c3c(Cc4ccccc4)nnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8656 | 3-benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)cinnoline | 6.54 |
Scaffold Activities Statistic