8659 : 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-2-yl)methyl]aniline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8659 |
| Name | 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-2-yl)methyl]aniline |
| smile | CN1C(=CC2=CC=CC=C12)CNC1=CC=CC(C2=C(C=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1 |
| weight | 522 |
| scaffold ID | 706 |
| scaffold smile | c1c2ccccc2[nH]c1CNc1cccc(-c2c(Cc3ccccc3)cnc3ccccc32)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8659 | 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-2-yl)methyl]aniline | 10.18 |
Scaffold Activities Statistic