8668 : 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-7-yl)methyl]aniline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8668 |
| Name | 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-7-yl)methyl]aniline |
| smile | CN1C=CC2=CC=CC(=C12)CNC1=CC=CC(C2=C(C=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1 |
| weight | 522 |
| scaffold ID | 1000 |
| scaffold smile | c1cc2cccc(CNc3cccc(-c4c(Cc5ccccc5)cnc5ccccc54)c3)c2[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8668 | 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methyl-1H-indol-7-yl)methyl]aniline | 4.17 |
Scaffold Activities Statistic