8712 : 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}-2-ethylbutanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8712 |
| Name | 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}-2-ethylbutanoic acid |
| smile | CCC(C1=CC=CC(=C1)OCCCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1)(C(O)=O)CC |
| weight | 638 |
| scaffold ID | 147 |
| scaffold smile | c1ccc(CN(CCCOc2ccccc2)CC(c2ccccc2)c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8712 | 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}-2-ethylbutanoic acid | 0.174 |
Scaffold Activities Statistic