8719 : 2-(3-{[(2S)-4-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butan-2-yl]oxy}phenyl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8719 |
| Name | 2-(3-{[(2S)-4-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butan-2-yl]oxy}phenyl)acetic acid |
| smile | C[C@H](OC1=CC=CC(=C1)CC(O)=O)CCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1 |
| weight | 596 |
| scaffold ID | 147 |
| scaffold smile | c1ccc(CN(CCCOc2ccccc2)CC(c2ccccc2)c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8719 | 2-(3-{[(2S)-4-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butan-2-yl]oxy}phenyl)acetic acid | 0.145 |
Scaffold Activities Statistic