8721 : 2-{2-[2-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)ethyl]-1-benzofuran-5-yl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8721 |
| Name | 2-{2-[2-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)ethyl]-1-benzofuran-5-yl}acetic acid |
| smile | OC(CC1=CC=C2OC(=CC2=C1)CCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1)=O |
| weight | 592 |
| scaffold ID | 148 |
| scaffold smile | c1c2ccccc2oc1CCN(Cc1ccccc1)CC(c1ccccc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8721 | 2-{2-[2-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)ethyl]-1-benzofuran-5-yl}acetic acid | 0.145 |
Scaffold Activities Statistic