8723 : 5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8723 |
| Name | 5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid |
| smile | OC(C1CCCC2=C(C=CC=C12)OCCCN(CC1=CC=CC(C(F)(F)F)=C1Cl)CC(C1=CC=CC=C1)C1=CC=CC=C1)=O |
| weight | 622 |
| scaffold ID | 1334 |
| scaffold smile | c1ccc(CN(CCCOc2cccc3c2CCCC3)CC(c2ccccc2)c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8723 | 5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | 0.026 |
Scaffold Activities Statistic