8739 : 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-methylbenzene-1-sulfonamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8739 |
| Name | 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-methylbenzene-1-sulfonamide |
| smile | CNS(C1=CC=CC(=C1)OC1=CC=CC(C2=C(C(C)C)N=C3C(=CC=CN23)Cl)=C1)(=O)=O |
| weight | 456 |
| scaffold ID | 274 |
| scaffold smile | c1nc2ccccn2c1-c1cccc(Oc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8739 | 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-methylbenzene-1-sulfonamide | 1.61 |
Scaffold Activities Statistic