8741 : 3-[3-(3-methanesulfonylphenoxy)phenyl]-2-(propan-2-yl)imidazo[1,2-a]pyridine-8-carbonitrile
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8741 |
| Name | 3-[3-(3-methanesulfonylphenoxy)phenyl]-2-(propan-2-yl)imidazo[1,2-a]pyridine-8-carbonitrile |
| smile | CC(C1N=C2C(C#N)=CC=CN2C=1C1=CC=CC(=C1)OC1=CC=CC(S(C)(=O)=O)=C1)C |
| weight | 432 |
| scaffold ID | 274 |
| scaffold smile | c1nc2ccccn2c1-c1cccc(Oc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8741 | 3-[3-(3-methanesulfonylphenoxy)phenyl]-2-(propan-2-yl)imidazo[1,2-a]pyridine-8-carbonitrile | 3.9 |
Scaffold Activities Statistic