8743 : 2-methyl-3-{3-[3-(propane-2-sulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8743 |
| Name | 2-methyl-3-{3-[3-(propane-2-sulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)imidazo[1,2-a]pyridine |
| smile | CC(S(C1=CC=CC(=C1)OC1=CC=CC(C2=C(N=C3C(C(F)(F)F)=CC=CN23)C)=C1)(=O)=O)C |
| weight | 475 |
| scaffold ID | 274 |
| scaffold smile | c1nc2ccccn2c1-c1cccc(Oc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8743 | 2-methyl-3-{3-[3-(propane-2-sulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)imidazo[1,2-a]pyridine | 4.1 |
Scaffold Activities Statistic