8746 : 3-(3-{3-[2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]phenoxy}benzenesulfonyl)propan-1-ol
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8746 |
| Name | 3-(3-{3-[2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]phenoxy}benzenesulfonyl)propan-1-ol |
| smile | CC1N=C2C(C(F)(F)F)=CC=CN2C=1C1=CC=CC(=C1)OC1=CC=CC(S(CCCO)(=O)=O)=C1 |
| weight | 491 |
| scaffold ID | 274 |
| scaffold smile | c1nc2ccccn2c1-c1cccc(Oc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8746 | 3-(3-{3-[2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]phenoxy}benzenesulfonyl)propan-1-ol | 6.0 |
Scaffold Activities Statistic