8761 : 1-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)piperidine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8761 |
| Name | 1-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)piperidine |
| smile | CS(C1=CC=CC(=C1)OC1=CC=CC(C2=C(N=C3C(C(F)(F)F)=CC=CN23)CN2CCCCC2)=C1)(=O)=O |
| weight | 530 |
| scaffold ID | 362 |
| scaffold smile | c1ccc(Oc2cccc(-c3c(CN4CCCCC4)nc4ccccn43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8761 | 1-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)piperidine | 0.92 |
Scaffold Activities Statistic