8795 : 4-[3-(2,4-difluoro-5-methanesulfonylphenyl)phenyl]-3-methyl-8-(trifluoromethyl)quinoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8795 |
| Name | 4-[3-(2,4-difluoro-5-methanesulfonylphenyl)phenyl]-3-methyl-8-(trifluoromethyl)quinoline |
| smile | CC1=CN=C2C(C(F)(F)F)=CC=CC2=C1C1=CC=CC(C2=CC(S(C)(=O)=O)=C(C=C2F)F)=C1 |
| weight | 477 |
| scaffold ID | 239 |
| scaffold smile | c1ccc(-c2cccc(-c3ccnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8795 | 4-[3-(2,4-difluoro-5-methanesulfonylphenyl)phenyl]-3-methyl-8-(trifluoromethyl)quinoline | 0.195 |
Scaffold Activities Statistic