8824 : 5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methyl-2-methylidene-9-azatricyclo[9.4.0.0³,?]pentadeca-1(15),3,5,7,11,13-hexaen-10-one
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8824 |
| Name | 5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methyl-2-methylidene-9-azatricyclo[9.4.0.0³,?]pentadeca-1(15),3,5,7,11,13-hexaen-10-one |
| smile | CN1C(C2=CC=CC=C2C(C2=CC(C(C(F)(F)F)(C(F)(F)F)O)=CC=C12)=C)=O |
| weight | 401 |
| scaffold ID | 100 |
| scaffold smile | C=C1c2ccccc2NC(=O)c2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8824 | 5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-9-methyl-2-methylidene-9-azatricyclo[9.4.0.0³,?]pentadeca-1(15),3,5,7,11,13-hexaen-10-one | 0.77 |
Scaffold Activities Statistic