8909 : (N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8909 |
| Name | (N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide) |
| smile | C1=CC=C(S(N(C2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)CC(F)(F)F)(=O)=O)C=C1 |
| weight | 481 |
| scaffold ID | 123 |
| scaffold smile | O=S(=O)(Nc1ccccc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8909 | (N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide) | 0.17 |
Scaffold Activities Statistic