8918 : 1,1,1,3,3,3-hexafluoro-2-[4-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]propan-2-ol (anilinohexafluoroisopropanol 22)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8918 |
| Name | 1,1,1,3,3,3-hexafluoro-2-[4-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]propan-2-ol (anilinohexafluoroisopropanol 22) |
| smile | CC1=C(CN(C2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)CC(F)(F)F)N=C(C2=CC(C(F)(F)F)=CC=C2)O1 |
| weight | 580 |
| scaffold ID | 250 |
| scaffold smile | c1oc(-c2ccccc2)nc1CNc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8918 | 1,1,1,3,3,3-hexafluoro-2-[4-[[5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]propan-2-ol (anilinohexafluoroisopropanol 22) | 0.1 |
Scaffold Activities Statistic