8942 : 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8942 |
| Name | 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid |
| smile | OC(CC1=CC=C(C=C1)COC1=CC=CC(C2=C(C=NC3=C2C=CC=C3C(F)(F)F)CC2=CC=CC=C2)=C1)=O |
| weight | 528 |
| scaffold ID | 35 |
| scaffold smile | c1ccc(COc2cccc(-c3c(Cc4ccccc4)cnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8942 | 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid | 0.09 |
Scaffold Activities Statistic