8954 : 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]-1,3-thiazol-5-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8954 |
| Name | 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]-1,3-thiazol-5-yl]acetic acid |
| smile | CCCC1=C(OCCCN(C2=NC=C(CC(O)=O)S2)C)C=CC2=C1ON=C2C(F)(F)F |
| weight | 457 |
| scaffold ID | 1429 |
| scaffold smile | c1csc(NCCCOc2ccc3cnoc3c2)n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8954 | 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]-1,3-thiazol-5-yl]acetic acid | 0.65 |
Scaffold Activities Statistic