8955 : 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrimidin-5-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8955 |
| Name | 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrimidin-5-yl]acetic acid |
| smile | CCCC1=C(OCCCN(C2=NC=C(CC(O)=O)C=N2)C)C=CC2=C1ON=C2C(F)(F)F |
| weight | 452 |
| scaffold ID | 509 |
| scaffold smile | c1noc2cc(OCCCNc3ncccn3)ccc12 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8955 | 2-[2-[methyl-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]amino]pyrimidin-5-yl]acetic acid | 0.47 |
Scaffold Activities Statistic