8957 : 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]-N,N-dimethylacetamide (anilinohexafluoroisopropanol 51)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8957 |
| Name | 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]-N,N-dimethylacetamide (anilinohexafluoroisopropanol 51) |
| smile | CCN(C(C1=CC=CC=C1)COCC(N(C)C)=O)C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1 |
| weight | 492 |
| scaffold ID | 247 |
| scaffold smile | c1ccc(CNc2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 8957 | 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]-N,N-dimethylacetamide (anilinohexafluoroisopropanol 51) | 0.26 |
Scaffold Activities Statistic