8967 : 2-[(1S)-5-{2-[2-(2H-1,3-benzodioxol-5-yl)-5-methyl-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8967 |
| Name | 2-[(1S)-5-{2-[2-(2H-1,3-benzodioxol-5-yl)-5-methyl-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | CC1SC(C2=CC=C3OCOC3=C2)=NC=1CCOC1=CC=C2[C@@H](CCC2=C1)CC(O)=O |
| weight | 438 |
| scaffold ID | 747 |
| scaffold smile | c1sc(-c2ccc3c(c2)OCO3)nc1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 8967 | 2-[(1S)-5-{2-[2-(2H-1,3-benzodioxol-5-yl)-5-methyl-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid | 1.21 |
Scaffold Activities Statistic