8985 : 5-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-1-[4-(trifluoromethyl)pyrimidin-2-yl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8985 |
| Name | 5-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-1-[4-(trifluoromethyl)pyrimidin-2-yl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CCOC1=CC=CC(=C1)CC1=C(C(O)=O)CCN(C2=NC=CC(C(F)(F)F)=N2)C1 |
| weight | 565 |
| scaffold ID | 835 |
| scaffold smile | c1oc(-c2ccccc2)nc1CCOc1cccc(CC2=CCCN(c3ncccn3)C2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 8985 | 5-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-1-[4-(trifluoromethyl)pyrimidin-2-yl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid | 0.644 |
Scaffold Activities Statistic