9004 : (2S,3S)-1-(4-tert-butylphenyl)-3-[(3-{2-[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-4-oxoazetidine-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 9004 |
| Name | (2S,3S)-1-(4-tert-butylphenyl)-3-[(3-{2-[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-4-oxoazetidine-2-carboxylic acid |
| smile | COC1=CC=C(C2OC(=C(N=2)CCOC2=CC=CC(=C2)C[C@H]2[C@@H](C(O)=O)N(C3=CC=C(C(C)(C)C)C=C3)C2=O)C)C=C1 |
| weight | 569 |
| scaffold ID | 82 |
| scaffold smile | O=C1C(Cc2cccc(OCCc3coc(-c4ccccc4)n3)c2)CN1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 9004 | (2S,3S)-1-(4-tert-butylphenyl)-3-[(3-{2-[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]ethoxy}phenyl)methyl]-4-oxoazetidine-2-carboxylic acid | 0.008 |
Scaffold Activities Statistic