9022 : (2R,3R)-1-(4-tert-butylphenyl)-3-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-4-oxoazetidine-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 9022 |
| Name | (2R,3R)-1-(4-tert-butylphenyl)-3-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-4-oxoazetidine-2-carboxylic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CCOC1=CC=CC(=C1)C[C@@H]1[C@H](C(O)=O)N(C2=CC=C(C(C)(C)C)C=C2)C1=O |
| weight | 539 |
| scaffold ID | 82 |
| scaffold smile | O=C1C(Cc2cccc(OCCc3coc(-c4ccccc4)n3)c2)CN1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 9022 | (2R,3R)-1-(4-tert-butylphenyl)-3-({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)-4-oxoazetidine-2-carboxylic acid | 5.4 |
Scaffold Activities Statistic