9500 : 2-[2-methyl-4-({5-[4-(trifluoromethoxy)phenyl]-4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 9500 |
| Name | 2-[2-methyl-4-({5-[4-(trifluoromethoxy)phenyl]-4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1=NC(=C(C2=CC=C(C=C2)OC(F)(F)F)S1)C1=CC=C(C(F)(F)F)C=C1 |
| weight | 584 |
| scaffold ID | 12 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 9500 | 2-[2-methyl-4-({5-[4-(trifluoromethoxy)phenyl]-4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid | 10.0 |
Scaffold Activities Statistic