9505 : 2-{2-methyl-4-[(4-{4-[methyl(propan-2-yl)carbamoyl]phenyl}-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl)methoxy]phenoxy}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 9505 |
| Name | 2-{2-methyl-4-[(4-{4-[methyl(propan-2-yl)carbamoyl]phenyl}-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl)methoxy]phenoxy}acetic acid |
| smile | CC(N(C(C1=CC=C(C2N=C(SC=2C2=CC=C(C=C2)OC(F)(F)F)COC2=CC=C(C(=C2)C)OCC(O)=O)C=C1)=O)C)C |
| weight | 615 |
| scaffold ID | 12 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 9505 | 2-{2-methyl-4-[(4-{4-[methyl(propan-2-yl)carbamoyl]phenyl}-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl)methoxy]phenoxy}acetic acid | 0.69 |
Scaffold Activities Statistic