9694 : 2-({2-ethyl-4-oxo-3-[(1S)-5-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]-3H,4H,5H-imidazo[4,5-c]pyridin-5-yl}methyl)benzonitrile
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 9694 |
| Name | 2-({2-ethyl-4-oxo-3-[(1S)-5-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]-3H,4H,5H-imidazo[4,5-c]pyridin-5-yl}methyl)benzonitrile |
| smile | CCC1=NC2C=CN(C(C=2N1[C@H]1CCC2=CC(C3=CC=CC=C3C3=NN=NN3)=CC=C12)=O)CC1=CC=CC=C1C#N |
| weight | 539 |
| scaffold ID | 889 |
| scaffold smile | O=c1c2c(ccn1Cc1ccccc1)ncn2C1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 9694 | 2-({2-ethyl-4-oxo-3-[(1S)-5-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]-3H,4H,5H-imidazo[4,5-c]pyridin-5-yl}methyl)benzonitrile | 0.685 |
Scaffold Activities Statistic