HIT 2.0

Herbal Ingredients' Targets Platform

HIT2.0 is a comprehensive searching and curation platform for herbal ingredients and target information based on literature evidences. The molecular target information involves those proteins being directly/indirectly activated or inhibited, protein binders, and enzymes whose substrates or products are interested compounds. Those up or down regulated genes are also included under the treatment of individual ingredient.

More importantly, HIT2.0 provides an online target-suggesting and curation platform via text-mining technology. The latest PubMed abstracts involving potential targets will be auto-retrieved for the queried compounds. Users can download abstracts for local use. Alternatively, uses can enter My-target curation system to check the detailed compound-target relationship and create the latest personal targeting profiles.


                                                   





Source
Herbs
1,250
Herbal
Ingredients
1,237
Biological
Targets
2,208
Ingredient-Target
pairs
10,031
Therapeutic
Targets
1,231
Micro RNA
Targets
56



Claim: HIT is strictly for academic use only. Any commercial application should contact us at hit2.0@outlook.com.

Citation:
[1]. Hao Ye, Li Ye, Hong Kang, et al. HIT: linking herbal active ingredients to targets,  Nucleic Acids Research, Volume 39, Issue suppl_1, 1 January 2011, Pages D1055-D1059,  https://doi.org/10.1093/nar/gkq1165
[2]. Deyu Yan, Genhui Zheng, Caicui Wang, et al. HIT 2.0: an enhanced platform for Herbal Ingredients' Targets, Nucleic Acids Research, 2021, gkab1011, https://doi.org/10.1093/nar/gkab1011

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