Compound Description

ID:   C0001 Common name:   (-)-Demecolcine
IUPAC:  (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one CAS:  CAS:477-30-5
Chembl ID:   CHEMBL312862 Pubchem ID:   CID:220401
Formula:  C21H25NO5 TCM-ID:  TCMC10
Smiles:  CN[C@H]1CCc2c(c3c1cc(=O)c(cc3)OC)c(OC)c(c(c2)OC)OC
Alias:

Benzo[a]heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-, (S)-;

Colchamine;

Colchicine, N-deacetyl-N-methyl-;

(7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)benzo[a]heptalen-9(5H)-one;

Colchicine, N-deacetyl-N-methyl-, (-)-;

(-)-Colchamine;

(-)-Demecolcine;

(7S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one;

Alkaloid H 3, from Colchicum antumnale;

C 12669;

Ciba 12669A;

Colcemid;

Colchamin;

Deacetyl-N-methylcolchicine;

Deacetylmethylcolchicine;

Demecolcin;

Demecolcine;

Desacetylmethylcolchicine;

Desmecolcine;

Kolchamin;

N-Deacetyl-N-methylcolchicine;

N-Desacetyl-N-methylcolchicine;

N-Methyl-N-deacetylcolchicine;

N-Methyl-N-desacetylcolchicine;

N-Methyltri-O-methylcolchicinic acid;

NSC 3096;

Omain;

Omaine;

Reichstein's F;

Santavy's substance F;

Substance F
Structure:

Related Targets  (Total: 1)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 4)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0172 Lu Gen芦根 Common reed rhizomePhragmites communis
H0727 Ye Gan Cao野甘草 Sweet broomwortScoparia dulcis
H0739 Yi Yi Ren薏苡仁 Jobstears seedCoix lacryma- jobi var. ma - yuen
H1200 Bai Mao Gen白茅根 Lalang grass rhizomeImperata cylindrica