Compound Description

ID:   C0001 Common name:   (-)-Demecolcine
IUPAC:  (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one CAS:  CAS:477-30-5
Chembl ID:   CHEMBL312862 Pubchem ID:   CID:220401
Formula:  C21H25NO5 TCM-ID:  TCMC10
Smiles:  CN[C@H]1CCc2c(c3c1cc(=O)c(cc3)OC)c(OC)c(c(c2)OC)OC
Alias:

Benzo[a]heptalen-9(5H)-one, 6,7-dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-, (S)-;

Colchamine;

Colchicine, N-deacetyl-N-methyl-;

(7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)benzo[a]heptalen-9(5H)-one;

Colchicine, N-deacetyl-N-methyl-, (-)-;

(-)-Colchamine;

(-)-Demecolcine;

(7S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one;

Alkaloid H 3, from Colchicum antumnale;

C 12669;

Ciba 12669A;

Colcemid;

Colchamin;

Deacetyl-N-methylcolchicine;

Deacetylmethylcolchicine;

Demecolcin;

Demecolcine;

Desacetylmethylcolchicine;

Desmecolcine;

Kolchamin;

N-Deacetyl-N-methylcolchicine;

N-Desacetyl-N-methylcolchicine;

N-Methyl-N-deacetylcolchicine;

N-Methyl-N-desacetylcolchicine;

N-Methyltri-O-methylcolchicinic acid;

NSC 3096;

Omain;

Omaine;

Reichstein's F;

Santavy's substance F;

Substance F
Structure:

Related Targets  (Total: 1)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 4)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0172 Lu Gen芦根 Common reed rhizomePhragmites communis
H1200 Bai Mao Gen白茅根 Lalang grass rhizomeImperata cylindrica
H0727 Ye Gan Cao野甘草 Sweet broomwortScoparia dulcis
H0739 Yi Yi Ren薏苡仁 Jobstears seedCoix lacryma- jobi var. ma - yuen