Compound Description

ID:   C0241 Common name:   Naproxen
IUPAC:  (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid CAS:  CAS:22204-53-1
Chembl ID:   CHEMBL154 Pubchem ID:   CID:156391
Formula:  C14H14O3 TCM-ID:  TCMC1731
Smiles:  COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)O)C
Alias:

2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, (+)-;

2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, (S)-;

(αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid;

(+)-(S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid;

(+)-(S)-Naproxen;

(+)-2-(6-Methoxy-2-naphthyl)propionic acid;

(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid;

(+)-Naproxen;

(2S)-2-(6-Methoxy-2-naphthyl)propanoic acid;

(2S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid;

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid;

(S)-(+)-Naproxen;

(S)-(+)-Naproxene;

(S)-2-(6-Methoxy-2-naphthyl)propanoic acid;

(S)-2-(6-Methoxy-2-naphthyl)propionic acid;

(S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid;

(S)-2-(6-Methoxynaphthalen-2-yl)propionic acid;

(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid;

(S)-Naproxen;

(S)-α-Methyl-6-methoxynaphthalene-2-acetic acid;

Apo-Naproxen;

Aproxen;

Bonyl;

CG 3117;

Diocodal;

Dysmenalgit;

Equiproxen;

Floginax;

Laraflex;

Laser;

MNPA;

Naixan;

Napren;

Naprium;

Naprius;

Naprosyn;

Naprosyne;

Naproxen;

Naprux;

Naxen;

Nycopren;

Panoxen;

Prexan;

Proxen;

Proxine;

RS 3540;

Reuxen;

Veradol;

Xenar;

Xenar-CR;

d-2-(6-Methoxy-2-naphthyl)propionic acid;

d-Naproxen
Structure:

Related Targets  (Total: 11)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
A 2 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
A 2 Reference(s)
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
C 1 Reference(s)
T33OPP Interleukin-6IL6 P05231
C 1 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
C 1 Reference(s)
T16A2X CatalaseCAT P04040
C 1 Reference(s)
T88AJI Hypoxia-inducible factor 1-alphaHIF1A Q16665
C 1 Reference(s)
T80GUN 72 kDa type IV collagenaseMMP2 P08253
C 1 Reference(s)
T97TGY Cytochrome c oxidase subunit 8A, mitochondrialCOX8A P10176
C 1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
C 1 Reference(s)
T06IAI Collagen alpha-1(X) chainCOL10A1 Q03692
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens