Compound Description
| ID: C0303 | Common name: Phlorizin |
| IUPAC: 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one | CAS: CAS:60-81-1 |
| Chembl ID: CHEMBL245067 | Pubchem ID: CID:6072 |
| Formula: C21H24O10 | TCM-ID: TCMC1879 |
| Smiles: OC[C@H]1O[C@@H](Oc2cc(O)cc(c2C(=O)CCc2ccc(cc2)O)O)[C@@H]([C@H]([C@@H]1O)O)O | |
| Alias:
Phlorizin;
1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; Dihydrochalcone 2'-β-D-glucopyranoside; Floridzin; NSC 2833; Phloretin 2'-O-glucoside; Phloretin 2'-O-β-D-glucopyranoside; Phloretin 2'-glucoside; Phloretin 2'-β-D-Glucoside; Phloretin glucoside; Phlorhizin; Phloridzin; Phloridzosid; Phlorizine; Phlorizoside; Phlorrhizin |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T86J48 | Sodium/glucose cotransporter 1 | SLC5A1 |
P13866 |
A | 9 Reference(s) |
| T48DQY | Sodium/glucose cotransporter 2 | SLC5A2 |
P31639 |
A | 3 Reference(s) |
| T89YVM | Sodium-dependent glucose transporter 1 | MFSD4B |
Q5TF39 |
A | 1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
A | 1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
A | 1 Reference(s) |
| T11O8V | Angiopoietin-related protein 4 | ANGPTL4 |
Q9BY76 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 8)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0975 | Di Mian Cao | 地绵草 | NA | Euphorbia humifusa |
| H1056 | Fu Pen Zi | 覆盆子 | Red-and-Yellow garden raspberry | Rubus idaeus |
| H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
| H0974 | Di Jin Cao | 地锦草 | Humifuse euphorbia | Euphorbia humifusa |
| H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
| H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
| H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
| H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
Ckey description of the interaction between compound and target